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Horses

  • Methylprednisolone is given by mouth or injection and is used on and off label to treat inflammatory, immune-mediated, or hormonal conditions. Common side effects include increased drinking, urination, and appetite, dull/dry haircoat, and/or weight gain. Do not use in pets that are allergic to it, receiving NSAIDs, that are recovering from a recent surgery, or in pets with systemic fungal or viral infections, diabetes, Cushing’s disease, stomach or intestinal ulcers. If a negative reaction occurs, please call your veterinary office.

  • Methylsulfonylmethane is given by mouth and is used over the counter and off label to treat inflammatory conditions such as arthritis. Give as directed by your veterinarian. Side effects are uncommon but may include stomach upset, restlessness, or tiredness. Do not use in pets that are allergic to it or that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.

  • Omeprazole is given by mouth and is used off-label to treat ulcers and erosions in the stomach and upper small intestine. Give as directed. Side effects are uncommon but may include stomach upset, such as vomiting, diarrhea, or gas. Do not use in pets with a history of allergies to this class of drugs. If a negative reaction occurs, call your veterinarian.

  • Orbifloxacin is given by mouth and is used on and off label to treat certain susceptible bacterial infections. Give as directed by your veterinarian. The most common side effects include vomiting, diarrhea, and lack of appetite. Do not use in pets that are allergic to it or other quinolones, in growing pets, or in conjunction with cyclosporine. If a negative reaction occurs, please call your veterinary office.

  • Pentoxifylline is given by mouth and is used off label to treat skin disorders and poor perfusion due to inflamed blood vessels. Give as directed. Common side effects include vomiting, diarrhea, lack of appetite, excitement, or restlessness. Do not use in pets that are allergic to it, allergic to xanthines, or in pets with bleeding in the brain or eye. If a negative reaction occurs, please call your veterinary office.

  • Perna is given by mouth and is used over the counter to treat inflammatory conditions such as arthritis in cats, dogs, and horses. Give as directed by your veterinarian. The most common side effects are gastrointestinal effects such as nausea and diarrhea. Do not use in pets that are allergic to it or other shellfish, or in pregnant or nursing pets. If a negative reaction occurs, please call your veterinary office.

  • Phenobarbital is used off label and given by mouth or as an injection to treat seizures or to sedate your pet. Common side effects include sleepiness, increased thirst, urination, and/or appetite. Do not use this medication in pets with liver, lung, or kidney disease or those that are allergic to barbiturates. If a negative reaction occurs, please call your veterinary office.

  • Phenoxybenzamine is given by mouth and is used off label to treat urination difficulty related to sphincter tone, high blood pressure related to pheochromocytoma, and laminitis in horses. Phenoxybenzamine should be given as directed by your veterinarian. Common side effects include nausea, vomiting, diarrhea, small pupils, increased heart rate, and nasal congestion/stuffy nose. Do not use in pets that are allergic to it, in pets that cannot handle low blood pressure, or in horses with colic. If a negative reaction occurs, please call your veterinary office.

  • Phenylbutazone is given by mouth or injection and is used on and off label to treat pain and inflammation. Give as directed by your veterinarian. Serious side effects include skin sores, changes in eating/drinking, changes in urination, yellowing of the skin, gums, or eyes, swelling of the legs, weight loss, behavior change, or abnormal bleeding. Do not use in pets that are allergic to it or in pets with bone marrow disease, bleeding disorders, stomach or intestinal ulcers, or pregnancy. If a negative reaction occurs, please call your veterinary office.

  • Polysulfated glycosaminoglycan is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.